1/5/2024 0 Comments Acute trauma![]() A comprehensive review of the mechanisms underlying ATC has been published. Thus, early recognition accompanied by adequate and aggressive management of ATC would substantially reduce mortality and improve outcomes in severely injured patients. However, the adverse outcomes from uncontrolled non-surgical hemorrhage and disturbed hemostasis are not restricted to mortality only but also include organ dysfunction and loss due to prolonged hemorrhagic shock as well as the early termination of surgical procedures in order to save life. As each abnormality itself may substantially exacerbate the other, a downward spiral is initiated rapidly and accelerates to death. Most recently, Brohi et al emphasized the role of hypoperfusion for the initiation of ATC. To date, six key initiators of coagulopathy in trauma have been described as tissue trauma, shock, hemodilution, hypothermia, acidemia, and inflammation. Current literature suggests that acute traumatic coagulopathy (ATC) is multifactorial with certain mechanisms being predominant whereas others manifest only in specific clinical states ( Figure 1). These clinical observations together with recent research resulted in a new appreciation of the central role of coagulopathy in acute trauma care. Despite substantial improvement in acute trauma care, uncontrolled haemorrhage is responsible for over 50% of all trauma-related deaths within the first 48 hours after admission. Surgeons in this section see patients for trauma follow-up and general surgery care at the Stanford Healthcare Pavilion A in the main hospital. This website will provide access to contact information: Trauma Service.Trauma is the leading cause of death in persons aged 5 to 44 years and accounts for approximately 10% of all deaths in general. ![]() Our goal is to develop a patient-centered program that will address the needs of each patient but which will also enable us to address these larger issues and improve the results for all trauma patients.
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